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Usage: Xenical blocks absorption of dietary fat into the bloodstream, thereby reducing the number of calories you get from a meal. At the usual dosage level, it cuts fat absorption by almost one-third. Combined with a low-calorie diet, it is used to promote weight loss and discourage the return of unwanted pounds. Your diet should be nutritionally balanced and contain approximately 30% of its calories from fat. It is recommended that you take a fat-soluble multi-vitamin everyday because along with dietary fat, Xenical decreases the absorption of some fat-soluble vitamins and beta-carotene. To compensate, you should take a multivitamin containing vitamins A, E, D, and K once a day, at least 2 hours before or 2 hours after taking Xenical.
Directions: Xenical is taken with each meal (three times daily). Your daily fat intake should be divided equally between these three meals so you will benefit from Xenical's actions. Your medicine should be swallowed with water.
Side Effects: Side effects of Xenical are more common during the first year of treatment. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Xenical. More common side effects may include: Abdominal discomfort or pain, anxiety, arthritis, back pain, diarrhea, dizziness, earache, fatigue, fatty or oily stools, fecal urgency or incontinence, flu, gas with fecal discharge, gum problems, headache, increased defecation, menstrual problems, muscle pain, nausea, oily discharge, rectal discomfort or pain, respiratory tract infections, skin rash, sleep problems, tooth problems, urinary tract infections, vaginal inflammation, vomiting. Less common side effects may include: Dry skin, ear/nose/throat problems, joint disorders. Side effects that usually occur after the first year of treatment with Xenical include: depression, leg pain, swollen feet, and tendonitis.
Precautions: This medicine can cause changes in your bowel habits, such as fatty or oily stools, due to the elimination of undigested fat in your stool. Xenical reduces the absorption of supplements of some fat soluble nutrients, particularly beta-carotene and vitamin E. You should therefore follow your doctor's advice in taking a well balanced diet rich in fruit and vegetables. Xenical shouldn't be taken if you are pregnant, nursing, have food absorption problems or reduced bile flow.
Drug Interactions: If Xenical is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Xenical with the following:
Cyclosporine (Neoral and Sandimmune), Pravastatin (Pravachol), Warfarin (Coumadin).
If You Take Too Much: The results of a massive overdose of Xenical are unknown, although the drug seems relatively harmless. However, any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention.
Missed Dose: Resume taking Xenical at the next meal. Don''t try to make up the loss with a double dose. The extra drug won''t help.
Storage: Store at room temperature, in a tightly sealed container.
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